Comparing Cybin (NYSE:CYBN) & PepGen (NASDAQ:PEPG)

PepGen (NASDAQ:PEPG) and Cybin (NYSE:CYBN) are both medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, earnings, valuation, dividends, profitability, risk and analyst recommendations.

Volatility and Risk

PepGen has a beta of 1.69, indicating that its share price is 69% more volatile than the S&P 500. Comparatively, Cybin has a beta of 0.41, indicating that its share price is 59% less volatile than the S&P 500.

Analyst Ratings

This is a breakdown of current ratings and price targets for PepGen and Cybin, as reported by MarketBeat.com.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
PepGen	0	1	2	0	2.67
Cybin	0	0	3	0	3.00

PepGen currently has a consensus target price of $19.33, suggesting a potential upside of 106.55%. Cybin has a consensus target price of $50.50, suggesting a potential upside of 462.99%. Given Cybin’s stronger consensus rating and higher possible upside, analysts clearly believe Cybin is more favorable than PepGen.

Earnings & Valuation

This table compares PepGen and Cybin”s revenue, earnings per share and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
PepGen	N/A	N/A	-$78.63 million	($3.25)	-2.88
Cybin	N/A	N/A	-$35.93 million	($0.20)	-44.85

Cybin is trading at a lower price-to-earnings ratio than PepGen, indicating that it is currently the more affordable of the two stocks.

Institutional & Insider Ownership

58.0% of PepGen shares are owned by institutional investors. Comparatively, 17.9% of Cybin shares are owned by institutional investors. 4.6% of PepGen shares are owned by company insiders. Comparatively, 15.0% of Cybin shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Profitability

This table compares PepGen and Cybin’s net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
PepGen	N/A	-62.74%	-50.37%
Cybin	N/A	-109.05%	-97.85%

Summary

Cybin beats PepGen on 6 of the 11 factors compared between the two stocks.

About PepGen

PepGen Inc., a clinical-stage biotechnology company, focuses on the development of oligonucleotide therapeutics for use in the treatment of severe neuromuscular and neurologic diseases. Its lead product candidate is PGN-EDO51, an EDO peptide that is in Phase 2 clinical trial to treat Duchenne muscular dystrophy (DMD) patients. The company is also developing PGN-EDODM1, an EDO peptide-conjugated PMO, which is in Phase 1 clinical trial for the treatment of myotonic dystrophy type 1, as well as EDO therapeutic candidates, such as PGN-EDO53, PGN-EDO45, and PGN-EDO44 for the treatment of DMD. PepGen Inc. was founded in 2018 and is based in Boston, Massachusetts.

About Cybin

Cybin Inc., a clinical-stage biopharmaceutical company, focuses on developing psychedelic-based therapeutics for patients with mental health conditions. The company’s development pipeline includes CYB003, a deuterated psilocybin analog, which is in phase 1/2a clinical trial to treat major depressive disorder (MDD), as well as in preclinical trials for alcohol use disorder; CYB004, a deuterated dimethyltryptamine (DMT), which completed phase 2 clinical trial for treating generalized anxiety disorders; SPL028 injectable deuterated DMT completed phase 1 clinical intramuscular and intravenous trial; SPL026 completed phase 1, 1b, and 1/2a for MDD; and CYB005, a phenethylamine derivative, which in preclinical stage to treat neuroinflammation, as well as has a research pipeline of investigational psychedelic-based compounds. The company has research and collaboration agreement with TMS Neurohealth Centers Inc. for development of psychedelic compound-based therapeutics; Kernel for use of Kernel flow technology to measure neural activity; and Greenbook TMS to establish mental health centers. The company is headquartered in Toronto, Canada.